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Articles on Statistical Methods (2009 - 2024)

    * denotes a trainee

  • Bühler A*, Cook RJ and Lawless JF. Estimands and cumulative incidence function regression in clinical trials: some new results on interpretability and robustness.  CStatistics in Medicine. , 2024, 43 (29), 5513-5533.
  • Cook RJ and Lawless JF. Estimands in clinical trials of complex disease processes. Clinical Trials , 2024, 21 (5), 604-611.
  • Cook RJ and Lawless JF. Methodological challenges in studying disease processes using observational cohort data. Japanese Journal of Statistics and Data Science , 2024, 1–23.
  • Cook RJ and Lawless JF. Statistical and scientific considerations concerning the interpretation, replicability and transportabilityof research findings. The Journal of Rheumatology , 2024, 51 (2), 117–129.
  • Cook RJ and Moodie EEM. A retrospective and prospective study of biostatistics in Canada. The Canadian Journal of Public Health , 2024,
  • Mao F* and Cook RJ. Two-phase biomarker studies for disease progression with multiple registries. Journal of the Royal Statistical Society - Series C , 2024,
  • Mao F, Cheung L and Cook RJ. Two-phase designs with failure time processes subject to non-susceptibility. Biometrics , 2024, 80 (1).
  • Boher JM, Filleron T, Bunouf P and Cook RJ. Group sequential methods based on supremum logrank statistics under proportional and nonproportional hazards. Statistical Methods for Medical Research , 2024, 33 (7), 1137-1151.
  • Akkaya-Hocagil T*, Ryan LM, Cook RJ, Dang K-D, Carter RC, Richardson GA, Day NL, Coles CD, Carmichael Olson H, Jacobson SW and Jacobson JL. Benchmark dose profiles for bivariate exposures. Risk Analysis , 2024,
  • Li K*, Akkaya-Hocagil T*, Cook RJ, Ryan L, Dang KD, Carter C, Jacobson S, Jacobson J. Generalized propensity scores for causal analysis with multiple exposures. Statistics in Biosciences , 2024,
  • Yang C*, Diao L, Li X, Cook RJ. Regression trees for interval-censored failure time data based on censoring unbiased transformations and pseudo-observations. Canadian Journal of Statistics , 2024,

  • Dang K-D, Ryan LM, Akkaya-Hocagil T†, Cook RJ, Richardson GA, Day NL, Coles CD, Carmichael Olson H, Jacobson SW, Jacobson JL. Bayesian structural equation modeling for data from multiple cohorts: application to a meta-analysis of the effect of pre-natal alcohol on child cognition. Australian and New Zealand Journal of Statistics , 2023, 65 (3), 167-186.
  • Boher JM, Filleron T, Bunouf P and Cook RJ. New late-emphasis and combination tests based on infimum and supremum logrank statistics with application in oncology trials. Statistics in Medicine , 2023, 42 (12), 1981-1994.
  • Bühler A*, Cook RJ and Lawless JF. Multistate models as a framework for estimand specification in clinical trials of complex processes. Statistics in Medicine , 2023, 42 (9), 1368-1397.
  • Cuerden M*, Diao L, Cotton CA and Cook RJ. Doubly weighted mean score etimating functions with a partially observed effect modifier. Communications in Statistics: Theory and Methods , published online on January 19, 2023.
  • Dang K-D, Ryan LM, Cook RJ, Akkaya-Hocagil T*, Jacobson SW, Jacobson JL. Bayesian outcome selection modeling. STAT , 2023, 12 (1), e568.
  • Mao F* and Cook RJ. Two-phase designs with current status data. Statistics in Medicine , 2023, 42 (8), 1207-1232.

  • Akkaya-Hocagil T*, Ryan LM, Cook RJ, Jacobson SW, Richardson GA, Day NL, Coles CD, Carmichael Olson H, Jacobson JL. A hierarchical meta-analysis for settings involving multiple outcomes across multiple cohorts. STAT , 2022, 11 (1), e462.
  • Cuerden M*, Diao L, Cotton CA and Cook RJ. Doubly weighted estimating equations and weighted multiple imputation for causal inference with an incomplete subgroup variable. Biostatistics and Epidemiology , 2022, 6 (2): Special Issue on Causal Inference, 266-284.
  • Cheung LC, Albert PS, Das S, Cook RJ. Multistate models for the natural history of cancer progression. British Journal of Cancer , 2022, 127 , 1279-1288.
  • Cook RJ and Lawless JF. Life history analysis with multistate models: a review and some current issues. Canadian Journal of Statistics : Special Issue - 50th Aniversary of CJS, 2022, 50 (4), 1270-1298.
  • Cook RJ, Lawless JF, Xie B*. Marker-dependent observation and carry-forward of internal covariates in Cox regression. Lifetime Data Analysis: Special Issue Dedicated to David Oakes, 2022, 28 (4), 560-584.
  • Cook RJ, Lee K-A, Lo B, MacDonald RL. Classical regression and predictive modeling. World Neurosurgery , 2022, 161 , 251-264.
  • Diao L and Cook RJ. Nested doubly robust estimating equations for causal analysis with an incomplete effect modifier. Canadian Journal of Statistics , 2022, 50 (3), 776-794.
  • Jiang S and Cook RJ. Estimating the polytomous discrimination index for multistate processes under intermittent observation. Statistics in Medicine , 2022, 41 (19), 3661-3678.
  • Mao F* and Cook RJ. Spatial dependence modeling of latent susceptibility and time to joint damage in psoriatic arthritis. Biometrics , published online on October 13, 2022.
  • Wu Y* and Cook RJ. Assessing the accuracy of predictive models with interval-censored data. Biostatistics , 2022, 23 (1), 18-33.
  • Yang C*, Diao L, Cook RJ. Adaptive response-dependent two-phase designs: some results on robustness and efficiency. Statistics in Medicine , 2022, 41 (22), 4403-4425.

  • Akkaya-Hocagil T*, Cook RJ, Jacobson SW, Jacobson JL and Ryan LM. Propensity score analysis for a semi-continuous exposure variable: a study of gestational alcohol exposure and childhood cognition. Journal of the Royal Statistical Society: Series A (Statistics in Society) , 2021, 184 (4), 1390-1413.
  • Andersen PK, Perme MP, van Houwelingen HC, Cook RJ, Joly P, Martinussen T, Taylor JMG, Abrahamowicz M, Therneau TM for the STRATOS TG8 topic group. Analysis of time-to-event for observational studies: Guidance to the use of intensity models. Statistics in Medicine , 2021, 40 (1), 185-211.
  • Cook RJ and Lawless JF. Independence conditions and the analysis of life history studies with intermittent observation. Biostatistics , 2021, 22 (3), 455-481.
  • Jacobson JJ, Akkaya-Hocagil T*, Ryan LM, Dodge NC, Richardson GA, Olson HC, Coles CD, Day NL, Cook RJ, Jacobson SW. Effects of prenatal alcohol exposure on cognitive and behavioral development: findings from a hierarchical meta-analysis of data from six prospective longitudinal U.S. cohorts. Alcoholism: Clinical and Experimental Research , 2021, 45 (1), 2040-2058.
  • Jiang Y, Chiu C-Y, Yan Q, Chen W, Gorin MB, Conley YP, Lakhal-Chaieb ML, Cook RJ, Amos CI, Wilson AF, Bailey-Wilson JE, McMahon FJ, Vazquez AI, Yuan A, Zhong X, Xiong M, Weeks DE, Fan R. Gene-based association testing of dichotomous traits with generalized linear mixed models using extended pedigrees: Applications to age-related mascular degeneration. Journal of the American Statistical Association , 2021, 116 (534), 531-545.
  • Lee J* and Cook RJ. The illness-death model for family studies. Biostatistics , 2021, 22 (3), 482-503.
  • Yang C*, Diao L and Cook RJ. Survival trees for current status data. Proceedings of AAAI Spring Symposium on Survival Prediction - Algorithms, Challenges and Applications , 2021, PMLR 146 , 83-94.
  • Zhang B, Chiu C-Y, Yuan F, Sang T, Cook RJ, Wilson AF, Bailey-Wilson JE, Chew EY, Xiong M, Fan R. Gene-based analysis of bi-variate survival traits via functional regressions with applications to eye diseases. Genetic Epidemiology , 2021, 45 (5), 455-470.
  • Zhong Y and Cook RJ. Selection models for efficient two-phase design of family studies. Statistics in Medicine , 2021, 40 (2), 254-270.
  • Zhong Y and Cook RJ. Semiparametric recurrent event versus time-to-first-event analyses in randomized trials: estimands and model misspecification. Statistics in Medicine , 2021, 40 (16), 3823-3842.

  • Cook RJ and Lawless JF. Failure time studies with intermittent observation and losses to followup. Scandinavian Journal of Statistics , 2020, 47 (4), 1035-1063.
  • Jiang S* and Cook RJ. Composite likelihood for aggregate data from clustered multistate processes under intermittent observation. Communications in Statistics: Theory and Methods , 2020, 49 (12), 2913-2930.
  • Jiang S*, Cook RJ and Zeng L. Mitigating bias from intermittent measurement of time-dependent covariates in failure time analysis. Statistics in Medicine , 2020, 39 (13), 1833-1845.
  • Jiang S* and Cook RJ. A mixture model for bivariate interval-censored failure times with dependent susceptibility. Statistics in Biosciences , 2020, 12 , 37-62.
  • Lakhal-Chaieb L, Cook RJ and Zhong Y. Testing the heritability and parent-of-origin hypotheses for ages at onset of psoriatic arthritis under biased sampling. Biometrics , 2020, 76 (1), 293-303.
  • Shen H and Cook RJ. Regression with incomplete multivariate surrogate responses for a latent covariate. Journal of Biostatistics and Epidemiology , 2020, 4 (1), 247-264.
  • Zeng L, Cook RJ and Lee J*. Multistate analysis from cross-sectional and auxiliary samples. Statistics in Medicine , 2020, 39 (4), 387-408.

  • Chiu C-Y, Yuan F, Zhang B-S, Yuan A, Li X, Fang H-B, Lange K, Weeks DE, Wilson AF, Bailey-Wilson JE, Musolf AM, Stambolian D, Lakhal-Chaieb ML, Cook RJ, McMahon FJ, Amos CI, Xiong M, Fang R. Linear mixed models for association analysis of quantitative traits with next-generation sequencing data. Genetic Epidemiology , 2019, 43 (2), 189-206.
  • Chiu C-Y, Zhang B, Wang S, Shao J, Lakhal-Chaieb L, Cook RJ, Weeks DE, Lee M-L, Wilson AF, Bailey-Wilson JE, Xiong M, Fan R. Gene-based association analysis of survival traits via functional regression based mixed effect Cox models for related samples. Genetic Epidemiology , 2019, 43 (8), 952-965.
  • Jiang S* and Cook RJ. Score tests based on a finite mixture model of Markov processes under intermittent observation. Statistics in Medicine , 2019, 38 (16), 3013-3025.
  • Lawless JF and Cook RJ . A new perspective on loss to follow-up in failure time and life history studies. Statistics in Medicine , 2019, 38 (23), 4583-4610.
  • Lee J* and Cook RJ. On estimands arising from misspecified semiparametric rate-based analysis of recurrent episodic conditions. Statistics in Medicine , 2019, 38 (25), 4977-4998.
  • Lee J* and Cook RJ. Dependence modeling for multi-type recurrent events via copulas. Statistics in Medicine , 2019, 38 (21), 4066-4082.
  • Moon NC*, Zeng L and Cook RJ. Cohort study design for illness-death processes with disease status under intermittent observation. Biostatistics and Epidemiology , 2019, 3 (1), 178-200.
  • Sfumato P, Filleron T, Giorgi R, Cook RJ, Boher JM. Goftte: A R package for assessing goodness-of-fit in proportional (sub) distributions hazards regression models. Computational Methods and Programs in Biomedicine , 2019, 177 , 269-275.
  • Sun T, Liu Y, Cook RJ, Chen W, Ding Y. Copula-based score test for bivariate time-to-event data, with application to a genetic study of AMD progression. Lifetime Data Analysis , 2019, 25 (3), 546-568.
  • Zhong Y* and Cook RJ. The effect of omitted covariates in marginal and partially conditional recurrent event analyses. Lifetime Data Analysis , 2019, 25 (2), 280-300.

  • Jiang S* and Cook RJ. Cost-effective design of growth studies with aggregation and tracking. Journal of Biometrics and Biostatistics , 2018, 9 (3), 406. DOI: 10.4172/2155-6180.1000406
  • Moon N*, Zeng L and Cook RJ. Tracing studies in cohorts with attrition: selection models for efficient sampling. Statistics in Medicine , 2018, 37 (15), 2354-2366.
  • Wu Y* and Cook RJ. Variable selection and prediction in biased samples with censored outcomes. Lifetime Data Analysis , 2018, 24 (1), 72-93.
  • Zeng L, Cook RJ and Lee KA. Design of cancer trials based on progression-free survival with intermittent assessment. Statistics in Medicine , 2018, 37 (12), 1947-1959.
  • Zhong Y* and Cook RJ. Second-order estimating equations for clustered current status data from family studies using response-dependent sampling. Statistics in Biosciences , 2018, 10 (1), 160-183.

  • Boher JM, Filleron T, Giorgi R, Kramar A, Cook RJ. Goodness-of-fit test for monotone proportional subdistribution hazards assumptions based on weighted residuals. Statistics in Medicine , 2017, 36 (2), 362-377.
  • McIsaac MA* and Cook RJ. Statistical methods for incomplete data: some results on model misspecification. Statistical Methods for Medical Research , 2017, 26 (1), 248-267.
  • Wu Y* and Cook RJ. A two-phase model for chronic disease processes under intermittent observation. Statistics in Medicine , 2017, 36 (13), 2016-2031.

  • Boruvka A* and Cook RJ. Sieve estimation in a Markov illness-death process under dual censoring. Biostatistics , 2016 17 (2), 350-363.
  • Fan R, Wang Y, Yan Q, Ding Y, Weeks DE, Lu Z, Ren H, Cook RJ, Xiong M, Swaroop A, Chew EY, Chen W. Gene-based association analysis for censored traits via fixed effect functional regression. Genetic Epidemiology , 2016, 40 (2), 133-143.
  • Sutradhar R* and Cook RJ. A conditional frailty model for bivariate interval-truncated failure time data: an application to a study on siblings diagnosed with schizophrenia. Journal of Medical Statistics and Informatics , 2016, 4 , Article 1, 1-9. DOI: 10.7243/2053-7662-4-1
  • Zhong Y*¹ and Cook RJ. Augmented composite likelihood for copula modeling in family studies under biased sampling. Biostatistics , 2016, 17 (3), 437-452. (¹Winner of the 2015 Murray Martin Prize)

  • Aalen OO, Cook RJ and Roysland K. Does Cox analysis of a randomized survival study yield a causal treament effect? Lifetime Data Analysis , 2015, 21 (4), 579-593.
  • Boruvka A* and Cook RJ. A Cox-Aalen model for interval-censored data. Scandanavian Journal of Statistics , 2015, 42 (2), 414-426.
  • McIsaac MA* and Cook RJ. Adaptive sampling in two-phase designs: a biomarker study for progression in arthritis. Statistics in Medicine , 2015, 34 (21), 2899-2912.
  • Shen H* and Cook RJ. Analysis of interval-censored recurrent event processes subject to resolution. Biometrical Journal , 2015, 57 (5), 725-742.
  • Wu Y* and Cook RJ. Penalized regression for interval-censored times of disease progression: selection of HLA markers in psoriatic arthritis. Biometrics , 2015, 71 (3), 782-791.
  • Zeng L, Cook RJ, Wen L and Boruvka A*. Bias in progression-free survival analysis due to intermittent assessment of progression. Statistics in Medicine , 2015, 34 (24), 3181-3193.
  • Zhao J*, Cook RJ and Wu C. Multiple imputation for the analysis of incomplete compound variables. Canadian Journal of Statistics , 2015, 43 (2), 240-264.
  • Zhong Y* and Cook RJ. Sample size and robust marginal methods for cluster-randomized trials with censored event times. Statistics in Medicine , 2015, 34 (6), 901-923.

  • Cook RJ and Lawless JF. Statistical issues in modeling chronic disease in cohort studies. Statistics in Biosciences , 2014, 6 , 127-161.
  • Cotton CA, Wu Y* and Cook RJ. Correcting for sampling variation and measurement error in Cox regression with circulating tumour cells. Journal of Medical Statistics and Informatics , 2014, 2 (1), 1-10. DOI: 10.7243/2053-7662-2-1
  • Diao L* and Cook RJ. Composite likelihood for joint analysis of multiple multistate processes via copulas. Biostatistics , 2014, 15 (4), 690-705.
  • McIsaac MA* and Cook RJ. Response-dependent two-phase sampling designs for biomarker studies. Canadian Journal of Statistics , 2014, 42 (2), 268-284.
  • Shen H* and Cook RJ. A dynamic mover-stayer model for recurrent event processes subject to resolution. Lifetime Data Analysis , 2014, 20 (3), 404-423.
  • Wu L* and Cook RJ. Marginal methods for multivariate failure times under event-dependent censoring. International Journal of Statistics and Probability , 2014, 3 (3), 111-125. DOI: 10.5539/ijsp.v3n3p111
  • Zhong Y* and Cook RJ. Measurement error for age of onset in prevalent cohort studies. Applied Mathematics , 2014, 5 (11), 1672-1683. DOI: 10.4236/am.2014.511160

  • Cook RJ. Number needed to treat for recurrent events. Biometrics and Biostatistics , 2013, 4 (3), 1-6. DOI: 10.4172/2155-6180.1000167
  • Cook RJ. Authors' redress on `Robustness of methods for blinded sample size re-estimation with overdispersed count data' by Schneider et al. (2013). Statistics in Medicine , 2013, 32 (22), 3955-3957.
  • Cook RJ and Lawless JF. Concepts and tests for trend in recurrent event processes. Journal of the Iranian Statistical Society , 2013, 12 (1), 35-69.
  • Cook RJ, Lee K-A, Cuerden M* and Cotton CC. Inverse probability weighted estimating equations for randomized trials in transfusion medicine. Statistics in Medicine , 2013, 32 (25), 4380-4399.
  • Diao L*, Cook RJ and Lee K-A. A copula model for marked point processes. Lifetime Data Analysis , 2013, 19 (4), 463-489.
  • McIsaac MA*, Cook RJ and Poulin-Costello M. Incomplete data in randomized dermatology trials: Consequences and statistical methodology. Dermatology , 2013, 226 (1), 19-27.
  • Shen H* and Cook RJ. Regression with incomplete covariates and left-truncated time-to-event data. Statistics in Medicine , 2013, 32 (6), 1004-1015.
  • Wu L* and Cook RJ. The design of intervention trials involving recurrent and terminal events. Statistics in Biosciences , 2013, 5 (2), 261-285.

  • Chen B*, Yi GY, Cook RJ and Zhou X-H. Marginal methods for clustered longitudinal binary data with incomplete covariates. Journal of Statistical Planning and Inference , 2012, 142 (10), 2819-2831.
  • Lawless JF, Cigsar C and Cook RJ. Testing for monotone trend in recurrent event processes. Technometrics , 2012, 54 (2), 147-158.
  • Wu L* and Cook RJ. Misspecification of Cox regression models with composite endpoints. Statistics in Medicine , 2012, 31 (28), 3545-3561.

  • Chen B*, Yi GY and Cook RJ. Progressive multi-state models for informatively incomplete longitudinal data. Journal of Statistical Planning and Inference , 2011, 141 (1), 80-93.
  • Cook RJ and Bergeron P-J*. Information in the sample covariate distribution in prevalent cohorts. Statistics in Medicine , 2011, 30 (12), 1397-1409.
  • Cotton CA, Cuerden MS* and Cook RJ. Causal inference in nonrandomized studies via propensity score methods. Transfusion , 2011, 51 (12), 2536-2539.
  • Yi GY, Zeng L and Cook RJ. A robust pairwise likelihood method for incomplete longitudinal binary data arising in clusters. Canadian Journal of Statistics , 2011, 39 (1), 34-51.

  • Chen B*, Yi GY and Cook RJ. Analysis of interval-censored disease progression data via multi-state models under a nonignorable inspection process. Statistics in Medicine , 2010, 29 (11), 1175-1189.
  • Chen B*, Yi GY and Cook RJ. Weighted generalized estimating functions for longitudinal response and covariate data that are missing at random. Journal of the American Statistical Association , 2010, 105 (489), 336-353.
  • Cook RJ, Lawless JF and Lee K-A. A copula-based mixed Poisson model for bivariate recurrent events under event-dependent censoring. Statistics in Medicine , 2010, 29 (6), 694-707.
  • Cook RJ, Yi GY and Lee K-A. Sequential testing with recurrent events over multiple treatment periods. Statistics in Biosciences , 2010, 2 (2), 137-153.
  • Lakhal-Chaieb L, Cook RJ and Lin X. Inverse probability of censoring weighted estimates of Kendall's tau for gap time analyses Biometrics , 2010, 66 (4), 1145-1152.
  • Pullenayegum E* and Cook RJ. The analysis of treatment effects for recurring episodic conditions. Statistics in Medicine , 2010, 29 (14), 1539-1558.
  • Tolusso D* and Cook RJ. Local likelihood for right and interval censored recurrent event data. Advances and Applications in Statistical Sciences , 2010, 1 , 343-369.
  • Yi GY, Cook RJ, Chen B*. Estimating functions for evaluating treatment effects in cluster-randomized longitudinal studies in the presence of drop-out and non-compliance. Canadian Journal of Statistics , 2010, 38 (2), 232-255.
  • Zeng L, Cook RJ and Warkentin TE. Regression analysis with a misclassified covariate from a current status observation scheme. Biometrics , 2010, 66 (2), 415-425.

  • Chen BE* and Cook RJ. The analysis of multivariate recurrent events with partially missing event types. Lifetime Data Analysis , 2009, 15 (1), 41-58.
  • Chen B*, Yi GY and Cook RJ. Likelihood analysis of joint marginal and conditional models for longitudinal categorical data. Canadian Journal of Statistics , 2009, 37 (2), 182-205.
  • Cook RJ, Bergeron P-J*, Boher J-M*, Liu Y*. Two-stage design of clinical trials involving recurrent events. Statistics in Medicine , 2009, 28 (21), 2617-2638. [R program]
  • Cook RJ, Lawless JF, Lakhal-Chaieb L* and Lee K-A. Robust estimation of mean functions and treatment effects for recurrent events under event-dependent censoring and termination: Application to skeletal complications in cancer metastatic to bone. Journal of the American Statistical Association , 2009, 104 (485), 60-75.
  • Cook RJ and Tolusso D*. Second-order estimating equations for the analysis of clustered current status data. Biostatistics , 2009, 10 (4), 756-772.
  • Sutradhar R* and Cook RJ. A bivariate mover-stayer model for interval-censored recurrent event data: Application to joint damage in rheumatology. Communications in Statistics: Theory and Methods , 2009, 38 (18), 3389-3405.
  • Tolusso D* and Cook RJ. Robust estimation of state occupancy probabilities for interval-censored multistate data: An application involving spondylitis in psoriatic arthritis. Communications in Statistics: Theory and Methods , 2009, 38 (18), 3307-3325.

  • Cook RJ, Zeng L and Lee K-A. A multistate model for bivariate interval censored failure time data. Biometrics , 2008, 64 (4), 1100-1109.
 
Department of Statistics and Actuarial Science, 200 University Avenue West, Waterloo, Ontario, Canada N2L 3G1
Tel: (519) 888-4567 ext. 45549        Fax: (519) 746-1875        Email: rjcook at uwaterloo.ca